What gender-affirming medications does Plume prescribe?

Plume offers a number of medication options that will support you on your gender journey and help you feel like your best, most authentic self. Some of the medications our care providers prescribe include hormones (testosterone, estradiol, progesterone), hormone blockers (spironolactone, finasteride, dutasteride), hair loss medications (finasteride/dutasteride), and sexual function support medications (sidenafil, tadalafil). Your medical provider will create a customized treatment plan based on your goals and desires. 

Can I microdose?

Yes! “Microdosing” is a term that means using a less-than-standard dose of hormone therapies. Some people prefer to take smaller amounts of testosterone, estrogen, or an androgen blocker. Sometimes called a “low dose” or  “nonbinary dose”, these smaller amounts of hormones may allow for slower and/or more subtle changes in your body than the full amount. For example, taking a microdose of testosterone will affect your vocal pitch, but may not lower your voice as much as the full dose would. Some reasons to microdose is that you may want more time to determine the effects you want from GAHT, or just prefer the changes to happen more slowly. Bear in mind that microdosing does not eliminate the less-desirable side effects of some medications, such as mood changes, acne, and hair loss. Whatever your gender journey goals, Plume will support you while you find what works for you. There is no cookie-cutter answer to what is going to help you feel comfortable, so feel free to try the medications that feel right for you, ask questions, and learn more as you grow into yourself.


Do you prescribe syringes?

Yes, if you are prescribed an injectable medication, we will prescribe you needles and  syringes! You will get them at the pharmacy when you pick up your medications or will receive them in the mail with your prescription delivery. If you are interested in buying injection supplies in bulk, let your care team know! They will guide you through ordering them online through the proper medical supply websites, based on your current prescription. This can be a more affordable option, especially if you are not using insurance to help cover the cost of your supplies. If your pharmacy is having trouble getting the correct injection supplies in stock, you may also search for a local syringe exchange program near you as a potential alternative resource. Make sure you have enough needles and syringes on hand for your medication. You should use a new needle and syringe each time you inject.

What are the different ways I can take my medication?

For testosterone, Plume prescribes injectable testosterone, topical testosterone gel, and testosterone patches. Learn more about testosterone here.

For estrogen and E+ medications, we prescribe tablets (estradiol, progesterone, and testosterone blockers), patches, and injectable estradiol. Learn more about estrogen and E+ medications here.

For hair loss, we offer tablets and topical creams/foams. Learn more about how certain medications may affect your hair, skin, or create other changes here.